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本文采用肿瘤坏死因子单克隆抗体的 ELISA 法检测了72例丙型肝炎、丙型肝炎合并乙型肝炎及乙型肝炎患者血浆肿瘤坏死因子并测定其细胞诱生白细胞介素6的生物活性.结果发现,患者肿瘤坏死因子及白细胞介素6水平增高,尤以丙型肝炎病毒感染患者为甚.并且,患者肿瘤坏死因子和白细胞介素6呈显著相关.这一结果表明,肿瘤坏死因子和白细胞介素6在丙型肝炎病毒感染的致病原理中可能有一定意义.
In this paper, Tumor necrosis factor monoclonal antibody ELISA assay 72 cases of hepatitis C, hepatitis C and hepatitis B patients with plasma tumor necrosis factor and determine the cell-induced interleukin 6 biological activity.Results Found that patients with elevated levels of tumor necrosis factor and interleukin 6, especially in patients with hepatitis C virus infection is very high, and in patients with tumor necrosis factor and interleukin 6 was significantly correlated.This result shows that tumor necrosis factor and leukocytes Interleukin 6 may have some significance in the pathogenesis of hepatitis C virus infection.