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目的观察硝酸布康唑阴道乳膏治疗念珠菌性阴道病的疗效。方法选择单纯念珠菌性阴道病患者218例,其中治疗组110例,晚上临睡前用投药器将硝酸布康唑阴道乳膏5 g送放入阴道深处,每日1次,连用3 d,4~7 d使用硝酸布康唑阴道乳膏安慰剂;对照组108例,用同样方法将克霉唑阴道乳膏5 g送放入阴道深处,每日1次,连用7 d。两组患者分别于停药后4~10 d观察临床综合疗效等级,停药后28~35 d观察复发率。结果两组患者临床综合疗效等级及复发率差异无统计学意义(P>0.05)。结论硝酸布康唑阴道乳膏与克霉唑阴道乳膏在治疗念珠菌性阴道病上具有相同的疗效。
Objective To observe the efficacy of buconazole nitrate vaginal cream in the treatment of Candida vaginosis. Methods 218 cases of Candida vaginitis patients were selected, of which 110 cases in the treatment group, before going to sleep at night before going to bed with a drug delivery device 5 g buccal oxazoline nitrate vaginal cream sent deep into the vagina once daily for 3 d , 4 to 7 days with buconazole nitrate cream vaginal cream placebo; control group of 108 cases, the same method will clotrimazole vaginal cream 5 g into the vagina deep, once daily for 7 days. Two groups of patients were observed after 4 to 10 d of clinical efficacy of the clinical efficacy of 28 to 35 days after stopping to observe the recurrence rate. Results There was no significant difference in clinical efficacy and recurrence between the two groups (P> 0.05). Conclusions Butoconazole nitrate vaginal cream and clotrimazole vaginal cream in the treatment of Candida vaginosis have the same effect.