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目的探讨海马区肿瘤的临床病理特征及显微外科治疗的临床效果。方法对2002年6月至2006年8月进行手术治疗的14例海马区肿瘤病例的临床表现、病理类型、显微手术进行回顾性分析。结果14例中显微全切除11例,次全切除3例,术后无严重的并发症及手术死亡。术后Ⅱ级以上病例接受1个疗程的放疗,所有病例随访2～50个月,生存11例,恢复良好,死亡3例。结论海马区肿瘤以低级别胶质瘤为主,临床首发症状多为癫痫。由于其肿瘤源于古皮质和中间皮质,对邻近的结构不侵犯或很少侵犯,故在显微外科的原则下广泛切除可获得较好疗效。有癫痫者,宜结合癫痫手术原则手术。
Objective To investigate the clinicopathological features of tumors in the hippocampus and the clinical effects of microsurgery. Methods The clinical manifestations, pathological types and microsurgical findings of 14 cases of tumor in the hippocampus region from June 2002 to August 2006 were analyzed retrospectively. Results In 14 cases, microsurgical resection was performed in 11 cases and subtotal resection in 3 cases. No serious complications and surgical death occurred after operation. Patients with postoperative grade Ⅱ or higher received one course of radiotherapy. All patients were followed up for 2 to 50 months and survived in 11 cases, with good recovery and 3 deaths. Conclusion The tumors in the hippocampus are mainly low-grade gliomas. The first clinical symptom is epilepsy. Due to its tumor from the ancient cortex and the middle of the cortex, adjacent to the structure of non-infringement or infringement, so under the principle of microsurgery can get a better curative effect. Epilepsy, epilepsy surgery should be combined with the principle of surgery.