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目的探讨孟鲁司特钠与布地奈德联合治疗小儿咳嗽变异哮喘临床治疗效果。方法选自2011年6月至2013年12月在本院诊治咳嗽变异哮喘的患儿144例,将其随机分为两组,行布地奈德单药治疗72例患儿为对照组,行孟鲁司特钠和布地奈德联合治疗72例患儿为研究组,统计并分析两组患儿治疗疗效和相关指标情况。结果研究组患儿总有效率为94.4%,对照组患儿总有效率79.2%;研究组患儿各项临床指标、药物见效时间、复发率均优于对照组,差异有统计学意义(P<0.05)。结论针对咳嗽变异性哮喘患儿予以孟鲁司特钠联合布地奈德治疗效果明显,不良反应少,复发率低。
Objective To investigate the clinical effect of montelukast sodium and budesonide in the treatment of pediatric cough variant asthma. Methods From June 2011 to December 2013, 144 children with cough variant asthma in our hospital were randomly divided into two groups, 72 patients were treated with budesonide monotherapy as control group, The combined treatment of sodium Lustustine and budesonide 72 cases of children as study group, statistics and analysis of two groups of children treatment efficacy and related indicators. Results The total effective rate was 94.4% in the study group and 79.2% in the control group. The clinical indexes, the effective time and the recurrence rate in the study group were all better than those in the control group (P <0.05). Conclusion The treatment of patients with cough variant asthma with montelukast combined with budesonide has obvious curative effect, few side effects and low recurrence rate.