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目的了解南安市柳城社区成人糖尿病及糖尿病前期的流行病学特点。方法采用整群随机抽样方法,于2013年调查南安市柳城社区5个村委会常住居民(40岁及以上)4 756人,应答率89.4%。受试者隔夜空腹行口服葡萄糖耐量试验,检测空腹血糖及服糖后2 h血糖以分析其糖代谢情况。调查和分析糖尿病及糖尿病前期的相关危险因素。结果糖尿病及糖尿病前期患病率分别为13.7%(男性14.6%,女性12.9%)和14.4%(男性14.3%,女性14.6%);标化后分别为8.1%(男性8.5%,女性7.7%)和8.0%(男性7.8%,女性8.1%)。糖尿病及糖尿病前期的患病率均随年龄增长而升高(P<0.05)。多因素Logistic回归分析显示增龄、家族史、肥胖、血压升高、甘油三酯升高、总胆固醇升高为糖代谢异常的危险因素(OR=2.05、3.22、1.25、1.15、1.28、1.13,P<0.05)。高密度脂蛋白、规律运动是发生糖代谢异常的保护因素(OR=0.86、0.84,P<0.05)。结论南安市柳城社区糖尿病及糖尿病前期患病率相对较低,增龄、家族史、肥胖、高血压、高血脂是糖代谢异常的危险因素。须采取有效的防治策略以干预糖代谢异常的流行。
Objective To understand the epidemiological characteristics of adult diabetes and pre-diabetes in Liucheng community in Nan’an. Methods In a cluster random sampling method, 4 756 permanent residents (aged 40 and above) of 5 village committees in Liucheng community in Nanan City were investigated in 2013 with a response rate of 89.4%. Subjects underwent oral glucose tolerance test overnight fasting fasting blood glucose and blood sugar 2 h after taking the sugar to analyze its glucose metabolism. Investigate and analyze diabetes and pre-diabetes related risk factors. Results The pre-diabetes and pre-diabetes prevalence were 13.7% (14.6% for males and 12.9% for females) and 14.4% (14.3% for males and 14.6% for females), respectively; 8.1% (8.5% for males and 7.7% for females) And 8.0% (7.8% for males and 8.1% for females). Pre-diabetes and pre-diabetes prevalence increased with age (P <0.05). Multivariate logistic regression analysis showed that age, family history, obesity, elevated blood pressure, elevated triglycerides and elevated total cholesterol were risk factors for abnormal glucose metabolism (OR = 2.05, 3.22, 1.25, 1.15, 1.28, 1.13, P <0.05). High density lipoprotein and regular exercise were the protective factors of abnormal glucose metabolism (OR = 0.86, 0.84, P <0.05). Conclusion The prevalence of diabetes mellitus and pre-diabetes in Liucheng community in Nan’an is relatively low. Aging, family history, obesity, hypertension and hyperlipidemia are risk factors for abnormal glucose metabolism. To take effective prevention and treatment strategies to interfere with the prevalence of abnormal glucose metabolism.