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药物难治性部分性癫痫病人受累一侧作前颞叶切除手术后,80%可不再发病。但有些病人其病灶难以用脑电图(包括睡眠诱发及蝶骨电极)、CT 和磁共振影像(MR)所确定,但这些病人用氟—18—脱氧葡萄糖和正电子断层扫描(PCT)可发现发作间期脑受累侧局部糖代谢率降低,而后者又与局部脑血流量(rCBF)平行。rCBF 可用单光子发射CT(SPECT)测定,SPECT 用Xe~(133)或HMPAO 做示踪剂。本文则报导SPECT 对难治性部分性癫痫病人检查的结果并与其它神经影象检查做比较。
Drug refractory partial epilepsy patients involved in the affected side of the anterior temporal lobectomy surgery, 80% can no longer disease. However, in some patients, the lesions were difficult to identify with EEG (including sleep-induced and sphenoid electrodes), CT and magnetic resonance imaging (MR), but these patients were found to be found with fluoro- 18-deoxyglucose and positron emission tomography The rate of local glucose metabolism is decreased in the affected part of the interictal phase, which in turn is parallel to the regional cerebral blood flow (rCBF). rCBF can be detected by single photon emission CT (SPECT), SPECT Xe ~ (133) or HMPAO as tracer. This article reports the results of SPECT in patients with refractory partial epilepsy and compared with other neuroimaging tests.