论文部分内容阅读
帕金森氏病(PD)被公认为黑质致(?)部神经元的变性,已有作者报道这种变性与黑质的脂质过氧化物(lipid peroxidation)增高有关。Vit-E 作为一种不饱和脂质的抗氧化物,在维持生物膜的完整性和稳定性方面起着重要作用。作者为阐明Vit-E 在PD 发病机制中的作用,测定42例PD 患者及其配偶(对照组)血浆Vit—E 浓度和Vit—E/胆固醇比率,并进行比较。PD 组男22例,女20例,平均年龄67.3±1.34岁,发病平均年龄61.3±1.50岁。结果,PD 患者及其配偶血浆中Vit—E 平均浓度分别为13.84±0.56μg/ml 和14.80±0.57μg/ml,Vit-
Parkinson’s disease (PD) is recognized as a degeneration of neurons in the substantia nigra (?) That has been reported by authors to be associated with increased substantia nigra lipid peroxidation. Vit-E, as an unsaturated lipid antioxidant, plays an important role in maintaining the integrity and stability of biofilms. In order to clarify the role of Vit-E in the pathogenesis of PD, plasma Vit-E concentrations and Vit-E / cholesterol ratios were determined and compared in 42 patients with PD and their spouses (control group). PD group, 22 males and 20 females, the average age of 67.3 ± 1.34 years old, the average incidence of age was 61.3 ± 1.50 years. As a result, the average concentrations of Vit-E in plasma of patients with PD and their spouses were 13.84 ± 0.56 μg / ml and 14.80 ± 0.57 μg / ml, respectively. Vit-