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目的：探讨哌唑嗪特拉唑嗪控制嗜铬细胞瘤高血压的效果。方法：对１９７６ 年７ 月～１９９８年５ 月收治的１２ 例嗜铬细胞瘤围手术期用哌唑嗪和特拉唑嗪固定剂量和可调节剂量的降压效果进行回顾性小结。结果：治疗１０～１４ ｄ 后，血压由１６０／１２０ ｍ ｍ Ｈｇ（１ ｍ ｍ Ｈｇ＝ ０．１３３ ｋＰａ）降至１４０／９０ ｍ ｍ Ｈｇ，用药前后血压经统计学处理有极显著性差异（ Ｐ＜ ０．０１）。结论：哌唑嗪、特拉唑嗪治疗嗜铬细胞瘤的高血压是安全有效的，可以用于嗜铬细胞瘤的术前准备
Objective: To investigate the effect of prazosin terazosin on hypertensive pheochromocytoma. Methods: A retrospective summary of the perioperative use of prazosin and terazosin at fixed and adjustable doses in the perioperative period was performed in 12 pheochromocytomas treated from July 1976 to May 1998. RESULTS: After 10 to 14 days of treatment, the blood pressure decreased from 160/120 m m Hg (1 m m Hg = 0.133 kPa) to 140/90 m m Hg. There was a significant difference in blood pressure before and after treatment ( P<0.01). Conclusion: Prazosin and terazosin are safe and effective in the treatment of hypertension in pheochromocytoma and can be used for preoperative preparation of pheochromocytoma