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用过氧化物酶－抗过氧化物酶技术光镜下观察细胞性纤维连接蛋白（ＣＦＮ）在６３例肾母细胞瘤组织中表达强度与分布，探讨其与组织类型、预后之间的关系。结果，ＣＦＮ表达与瘤组织类型有关：上皮型，ＣＦＮ分布以肾小管样结构周围为主，而且表达强度高；间质型，ＣＦＮ多分布在细胞内，两者差异有显著意义（Ｐ＜０．０５）。ＣＦＮ表达情况与肿瘤的临床分期无关。当ＣＦＮ分布在细胞周围，表达强度高者，预后好，生存５年以上者多。ＣＦＮ表达可作为判定肾母细胞瘤预后的指标之一
The expression intensity and distribution of CFN in 63 cases of nephroblastoma were observed with peroxidase-anti-peroxidase technique, and the relationship between the expression and tissue type and prognosis was explored. The results showed that the expression of CFN was related to the type of tumor: epithelial type and CFN were mainly distributed around the tubular-like structure with high expression intensity; interstitial and CFN were more distributed in the cells, the difference was significant (P <0 .05). The expression of CFN has nothing to do with the clinical stage of the tumor. When CFN is distributed around the cells, the expression intensity is high, the prognosis is good, and those who survive for more than 5 years are more. CFN expression can be used as a prognostic indicator of nephroblastoma