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在原发性免疫缺陷症患者中有大量癌症发生的报道。作者报道原发性低丙神球蛋白血症,主要是普通可变免疫缺陷(Common Variable immunodef-iciency CVID)患者的前瞻性研究,包括医学研究委员会(MRC)早期研究的内容。本组共377例,为IgG 水平<300～100mg/dl 未满一岁患者,均接受过两种球蛋白治疗.最常见疾患为CVID,即所谓的“可变免疫缺陷”和“近期发作(或非家族的)的原发性低丙种球蛋白血症”。病例的确诊是在1957～1975年间用测血清IgG 水平得出,并随访至1981年9月1日,采取询问经管医师、
A large number of cancers have been reported in patients with idiopathic immunodeficiency. The authors report prospective studies of patients with idiopathic hypoccnoprotemia, primarily in patients with Common Variable immunodeficiency (CVID), including earlier studies by the Medical Research Council (MRC). This group of 377 patients with IgG levels <300 ~ 100mg / dl under the age of one year, had received two globulin treatment.The most common diseases CVID, the so-called “variable immune deficiency” and “recent seizures Or non-familial) primary hypogammaglobulinemia ”. The diagnosis of the case was obtained in 1957 ~ 1975 with serum IgG levels, and follow-up to September 1, 1981, taken to ask the administrator,