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目的探讨环磷腺苷对新生儿心肌受损的疗效。方法总结心肌受损患儿用环磷腺苷前后的临床表现及心肌酶谱,并与未用环磷腺苷的患儿对照。结果环磷腺苷治疗组有效率97.15%,对照组有效率65.54%,两组差异显著(P<0.01)。结论环磷腺苷对心肌有一定的保护作用,可改善预后,减少后遗症发生,临床疗效显著。
Objective To investigate the effect of cyclic adenosine monophosphate on neonatal myocardial damage. Methods The clinical manifestations and myocardial enzymes of patients with myocardial damage before and after use of cyclic adenosine monophosphate were compared with those of patients without cyclic adenosine monophosphate. Results The effective rate of cyclophosphamide treatment group was 97.15%, while that of the control group was 65.54%. There was significant difference between the two groups (P <0.01). Conclusions CAMP has a protective effect on myocardium, which can improve the prognosis and reduce the occurrence of sequelae. The clinical curative effect is remarkable.