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目的：观察小剂量米非司酮治疗子宫肌瘤的疗效。方法：依肌瘤大小将２３ 例子宫肌瘤患者分为三组，分别从月经第二天开始口服米非司酮５ｍ ｇ／ｄ，６．２５ｍ ｇ／ｄ 和８．３ｍ ｇ／ｄ，连用３ 个月，治疗前、期间及随访期间每月进行妇科检查和Ｂ超测量子宫径线，检查肝、肾功能和血色素。结果米非司酮５ｍ ｇ／ｄ 对２０ｍ ｍ ～２８ｍ ｍ 的肌瘤疗效较好，可使其消失；肌瘤较大时，米非司酮６．２５ｍ ｇ／ｄ，或８．３ｍ ｇ／ｄ，对其疗效无明显差别，肌瘤缩小较慢或停药后又增大，此外，肌瘤部位不同，疗效也不同，子宫颈部小肌瘤，５ｍ ｇ／ｄ 量即可使其消失，同一患者子宫体部肌瘤则缩小不显著；２ 例粘膜下肌瘤，在用药后均脱出于子宫口外。所有继发贫血患者，用药后贫血均得到纠正。结论：米非司酮治疗子宫肌瘤是安全有效的，该疗法是一种较有前途的治疗方法
Objective: To observe the efficacy of low-dose mifepristone in the treatment of uterine fibroids. Methods: According to the size of fibroids, 23 patients with uterine fibroids were divided into three groups. Mifepristone 5 m g / d, 6.25 m g / d and 8.3 m g / d were administered orally from the second day of menstruation respectively. 3 months, before treatment, during the period of follow-up and gynecological examination every month and B-measurement of uterine diameter line, check the liver and kidney function and hemoglobin. Results mifepristone 5m g / d on 20m m ~ 28m m fibroids better efficacy, can make it disappear; larger fibroids, mifepristone 6.25m g / d, or 8.3m g / d, no significant difference in its efficacy, slow fibroids shrink or stop after the increase, in addition, different parts of the fibroids, the curative effect is also different, small cervical fibroids, 5m g / d the amount can make it disappear , The same patients with uterine fibroids shrink is not significant; 2 cases of submucosal fibroids, after treatment are prolapsed in the uterus. All secondary anemia patients, after treatment of anemia have been corrected. Conclusion: Mifepristone treatment of uterine fibroids is safe and effective, the treatment is a more promising treatment