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磷是体内必需元素之一,正常成年人体内含磷700 g左右,85%以羟磷灰石的形式存在于骨骼和牙齿中,14%存在于细胞内,1%存在于细胞外液。磷在人体中有很重要作用,参与骨质的形成、以磷脂形式参与细胞膜的组成、与体内多种酶活性及能量代谢密切相关。体内正常血磷浓度为0.85~1.51mmol/L,当磷的浓度下降到0.32 mmol/L时,导致严重低磷血症~([1]),临床表现为横纹肌溶解、肢体感觉障碍、免疫力降低、呼吸困难、心力衰竭、构音障碍、饮食呛咳等~([2-3])。因此,对于严重
Phosphorus is one of the essential elements of the body, normal adult body contains about 700 g of phosphorus, 85% of hydroxyapatite in the form of bone and teeth, 14% exist in the cell, 1% exists in the extracellular fluid. Phosphorus plays a very important role in the human body and participates in the formation of bone mass. It participates in the composition of the cell membrane in the form of phospholipids, and is closely related to various enzyme activities and energy metabolism in the body. In vivo normal phosphorus concentration of 0.85 ~ 1.51mmol / L, when the phosphorus concentration dropped to 0.32 mmol / L, resulting in severe hypophosphatemia ~ ([1]), the clinical manifestations of rhabdomyolysis, limb sensory disturbances, immunity Reduce, dyspnea, heart failure, dysarthria, cough and other diet ~ ([2-3]). So for serious