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为了进一步了解目前流行性乙型脑炎 (乙脑 )灭活疫苗的免疫接种反应 ,在江苏省和上海市对 182 40 6接种人次进行了前瞻性调查。结果显示 ,乙脑灭活疫苗的一般接种反应发生率为 3 68% ,异常反应发生率为 2 0 96/ 10万～ 2 3 0 1/ 10万 ;主要临床表现以全身性过敏性皮疹反应为主 ;大年龄组的接种反应发生率明显高于小年龄组 ,有过敏史的对象接种易引发严重的接种反应。因此 ,要改善乙脑灭活疫苗的免疫接种反应状况 ,除了应提高疫苗的质量外 ,在实施免疫接种时应严格执行卫生部 1998年颁发的乙脑灭活疫苗免疫接种程序 ,以减少该疫苗的免疫接种反应。
In order to further understand the current immunization response of Japanese encephalitis (JE) inactivated vaccines, a prospective survey of 182 40 6 inoculations in Jiangsu Province and Shanghai was conducted. The results showed that the incidence of general inoculation of JE inactivated vaccine was 3 68%, and the incidence of abnormal reaction was 20 96/10 million to 23 0 1 10 000. The main clinical manifestations were systemic allergic rash reaction Lord; the incidence of vaccination in older age groups was significantly higher than the younger age group, vaccination of subjects with a history of allergies could lead to serious vaccination response. Therefore, in order to improve the immunization response of JE inactivated vaccine, in addition to improving the quality of vaccines, the vaccination program of JE inactivated vaccine issued by the Ministry of Health in 1998 should be strictly implemented to reduce the vaccine Immunization response.