Parlodel LAR对肿瘤性高PRL血症病人的长期治疗

• 作 者: 李波
• 出 处: 国外医学.妇产科学分册
• 发表日期: 1991年01期
• 关键词: 长效注射剂 溴隐亭 肿瘤性 微腺瘤 血症 泌乳素 预试验 耐受力 用药 肌注

口服溴隐亭有许多副作用,本文观察新型的溴隐亭长效注射剂(parlodel LAR)对肿瘤性高泌乳素(PRL)血症的治疗效果及其副作用。Parlodel LAR的载体降解较快(<3月),所以可重复注射。从预试验中了解到受试者对此药有较好的局部和全身耐受力,同时又能迅速及长时间(达28天)抑制PRL水平。本文观察6例PRL微腺瘤(均为女性)和8例PRL巨腺瘤(3例女性,5例男性)。ParlodelLAR每个月肌注1次,用药时间为早上8∶00,所

Oral bromocriptine has many side effects. In this paper, we observed the therapeutic effects and side effects of the new bromocriptine LAR on patients with hyperprolactinemia (PRL). The vector of Parlodel LAR degrades rapidly (<3 months), so it can be injected repeatedly. It was learned from the pilot study that the subjects had better local and systemic tolerance to this drug, while inhibiting the PRL level rapidly and for a long time (up to 28 days). In this study, 6 PRL microadenomas (all female) and 8 PRL giant adenomas (3 women and 5 men) were observed. ParlodelLAR intramuscular injection once a month, medication time is 8:00 in the morning