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为了探讨Ｄ二聚体（Ｄｄｉｍｅｒ，ＤＤ）与心、脑血管疾病的关系，采用ＥＬＩＳＡ双抗体夹心法对７２例心血管病人、５１例脑血管病人和７１例健康对照，进行了血浆Ｄ二聚体的测定。在年龄、性别等因素均衡的基础上，显示心、脑血管病例组的Ｄ二聚体含量分别为１１６ｍｇ／Ｌ和０８３ｍｇ／Ｌ，均显著高于对照组（０４３ｍｇ／Ｌ）。进一步将两病例组分为心肌梗塞、非心梗性冠心病、脑梗塞和脑出血亚型后，发现除了脑出血组外，其余三组的ＤＤ水平仍显著高于对照（Ｐ＜００５）。结果揭示Ｄ二聚体的检测在心、脑血管疾病发生中具有重要诊断价值，其含量可作为疗效观察和预后判断的指标之一。此外，根据Ｄ二聚体水平鉴别脑梗塞和脑出血的实际意义值得深入研究。
In order to investigate the relationship between D-dimer (DDimer) and cardiovascular and cerebrovascular diseases, 72 patients with cardiovascular disease, 51 patients with cerebrovascular disease and 71 healthy controls were studied by ELISA double antibody sandwich method. Plasma D dimer determination. On the basis of the balanced factors such as age and sex, the D-dimer contents of heart and cerebrovascular cases were 116mg / L and 083mg / L, respectively, which were significantly higher than those of the control group (043mg / L). Further divided the two cases into myocardial infarction, non-myocardial infarction, noninfarction coronary heart disease, cerebral infarction and intracerebral hemorrhage subtype, found that in addition to cerebral hemorrhage group, the remaining three groups of DD levels were still significantly higher than the control (P <0 05 ). The results revealed that D-dimer detection in the heart and cerebrovascular disease has an important diagnostic value, its content can be used as an indicator of efficacy and prognosis. In addition, according to D dimer level to identify the actual meaning of cerebral infarction and cerebral hemorrhage deserved further study.