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目的分析2013年媒体报道的乙型肝炎疫苗(Hepatitis B Vaccine,Hep B)事件中,湖南省3例接种Hep B后出现的疑似预防接种异常反应(Adverse Events Following Immunization,AEFI),为今后AEFI的处理提供参考。方法根据现场调查、临床资料及婴儿尸检报告、疫苗检验结果等进行分析。结果 2例接种Hep B后死亡,均为其他原因所致,与接种Hep B无关;1例接种Hep B同时注射1剂维生素K1,过敏性休克可能性大,过敏原是Hep B还是维生素K1无法确定。结论及时、客观的处理AEFI,适时发布权威信息,对于增加公众信任,减少社会负面影响,保持预防接种有序开展有重要作用。
Objective To analyze the adverse reactions of AEFI (Adverse Events Following Immunization) in Hepatitis B Vaccine (Hep B) reported by the media in 2013 in Hunan Province. Processing for reference. Methods According to field survey, clinical data and autopsy reports, vaccine test results were analyzed. Results Two patients died after vaccination with Hep B, all of which were caused by other causes, not related to the vaccination of Hep B. One patient was injected with Hep B and one vitamin K1 at the same time. The possibility of anaphylactic shock was high. Hep B or vitamin K1 was not allergen determine. Conclusion The timely and objective treatment of AEFI and the timely publication of authoritative information play an important role in increasing public trust, reducing the negative impact of the society and maintaining the orderly prevention and vaccination.