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目的探讨CT引导下活检联合靶向治疗在肺部炎性病变中的临床应用价值。方法搜集26例经活检确诊但临床治疗效果不佳的肺部炎性病变患者,再次行CT引导下活检联合靶向治疗,分析CT靶向治疗效果,并进一步提高活检的阳性率。结果 26例中,有21例检查结果与初诊结果一致,治疗后复查显示,16例治愈或好转,3例无明显变化,2例进展;5例诊断结果与初诊不相符,其中,合并肺腺癌2例,小细胞肺癌1例,肺真菌感染2例。并发症为少量气胸2例,少量咯血3例,没有发生致命性并发症。结论 CT引导下活检联合靶向治疗对临床保守治疗效果不佳的肺部炎性病变有着重要的临床意义。
Objective To investigate the clinical value of CT-guided biopsy combined with targeted therapy in the treatment of pulmonary inflammatory diseases. Methods Twenty-six patients with pathologically confirmed pulmonary inflammatory disease who were diagnosed biopsy but poorly treated were retrospectively analyzed. CT-guided biopsy combined with targeted therapy was performed to evaluate the efficacy of CT-targeted therapy and to further improve the positive rate of biopsy. Results Among the 26 cases, 21 cases were consistent with those of the newly diagnosed cases. After treatment, 16 cases were cured or improved, 3 cases showed no significant change and 2 cases progressed. The diagnosis of 5 cases did not accord with the initial diagnosis. Among them, 2 cases of cancer, 1 case of small cell lung cancer, 2 cases of pulmonary fungal infection. Complications for a small amount of pneumothorax in 2 cases, a small amount of hemoptysis in 3 cases, no fatal complications. Conclusion CT-guided biopsy combined with targeted therapy has clinical significance in the treatment of pulmonary inflammatory lesions with poor clinical efficacy.