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目的:观察米非司酮在绝经后妇女取环中的应用效果。方法:将260例绝经后要求取环的妇女260例妇女随机分为观察组和对照组各130例,例观察组术前3天给予米非司酮口服。2组术前均用2%的利多卡因棉球置宫颈管表面麻醉后取环。结果:参照WHO规定疼痛分级,观察组130例中0级76例,Ⅰ级23例,Ⅱ级29例,Ⅲ级2例;对照组130例中0级15例,Ⅰ级29例,Ⅱ级59例,Ⅲ级27例。观察组绝经后妇女取环疼痛程度明显低于对照组,P<0.05。观察组130例中取环顺利者119例(91.5%),困难者10例(7.7%),失败者1例(0.8%);对照组130例中取环顺利者87例(66.9%),困难者42例(32.3%),失败者1例(0.8%)。观察组绝经后妇女取环效果明显优于对照组,P<0.05。结论:米非司酮扩张宫颈效率高,能提高取环效果,减轻手术痛苦,可作为绝经后妇女取环前的预处理方法。
Objective: To observe the effect of mifepristone on the fetus in postmenopausal women. Methods: Two hundred and sixty 260 women who were asked to take the ring after menopause were randomly divided into observation group (130 cases) and control group (130 cases). The observation group was orally administered with mifepristone 3 days before the operation. 2 groups were preoperatively with 2% lidocaine cotton ball placed cervical canal surface anesthesia after ring. Results: According to the WHO classification of pain, the observation group included 130 cases of grade 0 in 76 cases, grade Ⅰ in 23 cases, grade Ⅱ in 29 cases and grade Ⅲ in 2 cases. In the control group, 130 cases were classified as grade 0 in 15 cases, grade Ⅰ in 29 cases and grade Ⅱ 59 cases, Ⅲ grade 27 cases. The observation group postmenopausal women taking ring pain was significantly lower than the control group, P <0.05. In the observation group, 119 patients (91.5%) were successful in taking the ring, 10 patients (7.7%) had failure, and 1 patient (0.8%) failed. In the control group, 87 patients (66.9% 42 patients (32.3%) were in difficulty, and 1 patient (0.8%) failed. Observation group, postmenopausal women was significantly better than the control group, P <0.05. Conclusion: Mifepristone has high efficiency of cervical dilatation, which can improve the effect of taking ring and relieve the pain of operation. It can be used as a pretreatment method for premenopausal women.