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目的了解山东省1～59岁人群乙型肝炎(乙肝)疫苗(Hepatitis B Vaccine,HepB)接种情况,为完善乙肝预防控制策略提供参考。方法2006年,对全省1～59岁人群HepB接种情况进行现况调查。采用多阶段随机抽样方法确定调查对象,通过查阅预防接种证/卡(对1～14岁儿童)或被调查者回忆获得免疫史,计算权重调整后接种率。结果全省1～59岁人群HepB全程接种率为27.07%[95%可信区间(Confidence Interval,CI)22.56%～31.59%],其中1～4岁儿童为99.66%(95%CI99.72%～100.00%),5～14岁儿童为89.95%(95%CI87.69%～92.20%),15～59岁人群为13.21%(95%CI7.78%～18.65%),各年龄组人群HepB全程接种率差异有显著的统计学意义(P<0.05)。不同性别和居住地人群HepB全程接种率差异无显著的统计学意义(P>0.05)。1～14岁儿童HepB首针(HepB1)及时接种率为65.41%(95%CI55.56%～75.25%);HepB1及时接种率随年龄增长而降低,1岁儿童最高为93.07%(95%CI88.43%～97.70%)。结论为进一步加强乙肝控制,山东省需对大年龄儿童开展HepB查漏补种,同时加强高危人群接种。
Objective To understand the inoculation of Hepatitis B Vaccine (Hepatitis B Vaccine) in Shandong Province from 1 to 59 years old, so as to provide a reference for improving the prevention and control strategy of Hepatitis B virus. Methods In 2006, the current situation of HepB inoculation among 1 ~ 59 years old population in the province was investigated. The multi-stage random sampling method was used to determine the subjects and the weight-adjusted vaccination rate was calculated by referring to the vaccination certificate / card (for children 1 to 14 years old) or the recall history of the respondents. Results HepB vaccination rate was 27.07% [95% CI (CI) 22.56% ~ 31.59%] in the population from 1 to 59 years old among whom 99.66% (95% CI 99.72% ~ 100.00%), 89.95% (95% CI 87.69% ~ 92.20%) in children aged 5 ~ 14, 13.21% (95% CI 7.78% ~ 18.65%) in 15- 59 years old, HepB The whole vaccination rate difference was statistically significant (P <0.05). There was no significant difference in the whole vaccination rate of HepB between different sexes and resident populations (P> 0.05). The timely vaccination rate of HepB1 was 65.41% (95.5% CI 55.56% -75.25%) in children aged 1-14 years. The timely vaccination rate of HepB1 decreased with age, the highest was 93.07% (95% CI 88 .43% ~ 97.70%). Conclusion In order to further strengthen the control of hepatitis B, it is necessary to carry out HepB screening and replanting in older children in Shandong Province, and to strengthen the vaccination of high-risk groups.