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本文用鲎试剂─合成基质偶氮显色法对90例流行性出血热（EHF）病人进行血浆内毒素定量检测。90例病人共检测了238份血浆标本，同时检测30例健康人血浆作为正常对照。血浆内毒素的正常值为50ng／L。88例病人血浆内毒素升高（大于50ng／L）。病人血浆内毒素越高，临床症状及体征越重。在EHF各期内毒素含量不同。在低血压期和少尿期内毒素浓度升高具有显著意义；发热期和多尿期内毒素轻度升高，恢复期内毒素含量正常。结果显示，EHF病人临床特征与血浆内毒素的含量有关。检测EHF病人的内毒素对揭示其发病机理、判断预后和指导治疗均有重要意义。
In this paper, 90 samples of hemorrhagic fever with hemorrhagic fever (EHF) were assayed for plasma endotoxin quantitatively by using the azo-chromogenic reagent azo complex. A total of 238 plasma samples were detected in 90 patients, and 30 healthy volunteers were also tested as normal controls. Normal plasma endotoxin is 50 ng / L. 88 patients increased plasma endotoxin (greater than 50ng / L). Patients with higher plasma endotoxin, clinical symptoms and signs of heavier. The levels of toxins varied during the EHF phase. During low blood pressure and oliguria period toxins concentration has significant significance; fever and polyuria endotoxin mild increase in the recovery period toxins normal. The results showed that the clinical characteristics of EHF patients and plasma endotoxin content. Detection of endotoxin in patients with EHF reveals its pathogenesis, prognosis and guidance of treatment are of great significance.