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有上消化道症状的101例患者分别作胃镜检查及钳取胃粘膜进行快速尿素酶检查，按内镜下表现将他们分为四组，I组（n＝18）：胃底部有炎症改变，而胃窦都无炎症改变；Ⅱ组（n＝36）：胃底部无炎症改变，而胃霎部有炎症改变；Ⅲ组（n＝26）：胃底、胃霎部均有炎症改变；Ⅳ组（n＝21）：胃底、胃窦部均无炎症改变。结果：Ⅰ、Ⅱ、Ⅲ、Ⅳ组胃底部幽门螺杆菌（HP）感染阳性率分别为66．67％、33．33％、65．39％、28．57％，Ⅰ组HP感染情况较Ⅱ、Ⅳ组明显增高（P＜0．05），Ⅲ组HP感染情况亦明显高于Ⅱ、Ⅳ组（P＜0．05），Ⅱ、Ⅳ组胃底HP感染情况相近（P＞0，05），Ⅰ、Ⅲ组胃底HP感染情况也相近（P＞0．05），这些说明胃底胃炎与胃底HP感染相关：Ⅰ、Ⅱ、Ⅲ、Ⅳ组胃窦部HP感染阳性率分别为66．67％、63．89％、69．73％、33．33％。Ⅰ、Ⅱ、Ⅲ组胃窦HP感染情况均明显高于Ⅳ组（P＜0．05），说明胃部炎症病人胃窦HP感染情况明显高于正常粘膜组。所有患者胃底、胃窦部HP感染阳性率分别为45．53％、59．41％，表现出良好的相关性（P＞0．05）。结果表明：HP为胃底胃炎的致病因素，胃底炎可能是胃窦炎症进展的结果，对胃底胃炎的治疗，应选用抗生素根除HP。
101 patients with upper gastrointestinal symptoms were examined by endoscopy and forceps mucosa for rapid urease test, they were divided into four groups according to endoscopic performance, group I (n = 18): changes in the bottom of the stomach inflammation (N = 36): no changes of inflammation in gastric fundus and inflammation in gastric ulcer; group Ⅲ (n = 26): inflammatory changes in gastric fundus and gastric ulcer ; Ⅳ group (n = 21): gastric fundus, gastric antrum no inflammatory changes. Results: The positive rates of Helicobacter pylori (HP) infection in gastric fundus of group Ⅰ, Ⅱ, Ⅲ and Ⅳ were 66.67%, 33.33%, 65.39% and 28.57%, respectively. (P <0.05). The HP infection in group Ⅲ was also significantly higher than that in group Ⅱ and Ⅳ (P <0.05), while the infection of HP in group Ⅱ and Ⅳ was similar (P> 05). The prevalence of HP infection in gastric fundus of group Ⅰ and Ⅲ was also similar (P> 0.05), which indicated that gastric fundus was related to HP infection of gastric fundus. The positive rate of HP infection in gastric antrum was significantly higher in groups Ⅰ, Ⅱ, Ⅲ and Ⅳ 66.67%, 63.89%, 69.73%, 33.33%. The HP infection in gastric antrum in group Ⅰ, Ⅱ and Ⅲ was significantly higher than that in group Ⅳ (P <0.05), indicating that HP infection in gastric antrum was significantly higher in patients with gastric inflammation than in normal mucosa. The positive rates of HP infection in gastric fundus and gastric antrum of all patients were 45.53% and 59.41%, respectively, showing a good correlation (P> 0.05). The results showed that: HP is the causative factor of gastric gastritis, gastritis may be the result of the progress of gastric antrum inflammation. For the treatment of gastritis, antibiotics should be used to eradicate HP.