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目的探讨盐酸右美托咪啶复合舒芬太尼应用于小儿术后镇痛的有效性和安全性。方法选取2015年1月至2016年12月于黄河三门峡医院就诊并进行手术的患儿60例,随机分为2组:观察组30例(盐酸右美托咪啶+舒芬太尼),对照组30例(舒芬太尼),观察2组患者术前、术后的FLACC评分、药物使用拔管前后的Ramsay镇静评分、并发症发生率。结果观察组术后FLACC评分为(1.07±0.24)分,优于对照组的(3.72±1.35)分(P<0.05);观察组拔管后Ramsay镇静评分为(2.77±1.04)分,优于对照组的(1.79±0.27)分(P<0.05);观察组患者并发症发生率为4.00%与对照组5.33%差异无统计学意义(P>0.05)。结论盐酸右美托咪啶复合舒芬太尼应用于小儿术后镇痛效果满意,不良反应相对减少。
Objective To investigate the efficacy and safety of dexmedetomidine hydrochloride combined with sufentanil for postoperative analgesia in children. Methods Sixty children admitted to Sanmenxia Hospital of the Yellow River from January 2015 to December 2016 were randomly divided into two groups: observation group (dexmedetomidine hydrochloride + sufentanil), control group 30 patients (sufentanil), the two groups of patients before and after FLACC score, drug use before and after extubation Ramsay sedation score, the incidence of complications. Results The postoperative FLACC score of the observation group was (1.07 ± 0.24) points, which was better than that of the control group (3.72 ± 1.35) points (P <0.05). The Ramsay sedation score of the observation group after extubation was (2.77 ± 1.04) (1.79 ± 0.27) points in the control group (P <0.05). There was no significant difference in the complication rate between the observation group and the control group (4.00% vs 5.33%, P> 0.05). Conclusion Dexmedetomidine hydrochloride combined with sufentanil is effective in postoperative analgesia in children, with a corresponding reduction in adverse reactions.