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目的 :观察扁桃体炎血清可溶性白细胞介素 2受体 (SIL- 2 R)水平及其临床意义。方法 :采用 EL ISA双抗夹心法检测 6 8例急慢性扁桃体炎及 6 8例正常人血清 SIL- 2 R水平。结果 :初发急性扁桃体炎及慢性扁桃体炎急性发作期患者 SIL - 2 R水平分别为 (6 42 .2± 87.2 )× 10 3u/ L ,(76 2 .3± 90 .5 )× 10 3u/ L ,均显著高于正常对照组的 (2 85 .5± 49.6 )× 10 3u/ L (P <0 .0 1) ,而且后者高于前者 (P <0 .0 1)。慢性扁桃体炎慢性期与正常对照无显著性差异 (P >0 .0 5 ) ,抗生素治疗 3～ 5 d后有效病例血清 SIL - 2 R明显下降。结论 :血清 SIL - 2 R测定对扁桃体炎诊断及疗效判定有一定意义。
Objective: To observe the serum levels of soluble interleukin 2 receptor (SIL-2 R) in tonsillitis and its clinical significance. Methods: Sixty-eight cases of acute and chronic tonsillitis and 68 cases of normal serum SIL-2R level were detected by ELISA. Results: The levels of SIL - 2R in patients with acute and chronic tonsillitis were (62.22 ± 87.2) × 10 3u / L and (76 2 ± 90.5) × 10 3u / L, respectively L were significantly higher than that of the control group (2 85.5 ± 49.6) × 10 3u / L (P <0.01), and the latter was higher than the former (P <0.01). There was no significant difference between the chronic stage of chronic tonsillitis and the normal control (P> 0.05), and the serum SIL - 2 R of the effective cases decreased obviously after 3 ~ 5 days of antibiotic treatment. Conclusion: The determination of serum SIL - 2 R has certain significance in the diagnosis and curative effect of tonsillitis.