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不同的麻醉药物组合用于小儿麻醉几十年却没有对药物接触和可能的毒性作用进行过系统评价。近年来,已建立在体和体外实验模型来评价多种麻醉药物不同剂量和接触时间相关的神经毒性,以及基因表达和蛋白质组学的研究、长期行为
Different narcotic combinations have been used in pediatric anesthesia for decades without a systematic review of drug exposure and possible toxic effects. In recent years, in vivo and in vitro experimental models have been established to evaluate the neurotoxicity associated with different doses and contact times of various narcotic drugs as well as studies of gene expression and proteomics, long-term behavior