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目的:探讨并发心房颤动(房颤)对冠心病患者经皮冠状动脉介入治疗(PCI)近期和远期临床结果的影响。方法:选择接受PCI治疗的冠心病患者3 893例,根据有无房颤分为无房颤组(A组,3 802例)和并发房颤组(B组,91例),分析房颤对冠心病患者PCI术后住院和随访期间不良心脑血管事件(MACCE)的影响。结果:A组与B组院内死亡、心肌梗死、脑卒中和再次血运重建发生率比较,差异无统计学意义;A组、B组随访时间中位数分别为535d、520d,B组MACCE发生率较A组有增高趋势(15.4%∶11.4%),主要为全因死亡率较高(5.7%∶1.7%,P=0.019),心肌梗死、脑卒中和再次血运重建发生率相当。结论:并发房颤的冠心病患者接受PCI术后的远期死亡率明显高于无房颤患者,房颤是预测PCI术后远期死亡率增高的独立危险因素。
Objective: To investigate the effect of concurrent atrial fibrillation (AF) on the clinical outcomes of patients with coronary artery disease undergoing percutaneous coronary intervention (PCI). Methods: A total of 3 893 CHD patients undergoing PCI were enrolled in this study. Atrial fibrillation (AF) was divided into three groups according to the presence or absence of atrial fibrillation (A group, 3 802 cases) and atrial fibrillation group (B group, 91 cases) Coronary heart disease patients after PCI and hospitalized during follow-up adverse cardiovascular and cerebrovascular events (MACCE). Results: There was no significant difference in the incidence of death, myocardial infarction, stroke and revascularization in hospital between group A and group B. The median follow-up time of group A and group B was 535 days and 520 days, respectively. MACCE occurred in group B The rate of all-cause mortality was higher (5.7%: 1.7%, P = 0.019), and the incidence of MI, stroke and revascularization was comparable. Conclusion: The long-term mortality after PCI in patients with coronary artery disease complicated with atrial fibrillation is significantly higher than that in patients without atrial fibrillation. Atrial fibrillation is an independent risk factor for predicting the long-term mortality after PCI.