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Background Primary intraspinal hemangiopericytoma is a rare malignant mesenchymal tumor with high rates ofrecurrence and metastasis.Surgery is the main therapeutic procedure for this lesion.This clinical research wasundertaken to analyze the pathological characteristics,clinical course,and the choice of treatment for this lesion.Methods Twenty-three patients with primary intraspinal hemangiopericytomas were treated from 1987 to 2004.Theclinical and imaging features,pathological findings,therapeutic procedures,and prognosis were analyzed retrospectively.Results Primary intraspinal hemangiopericytoma is more likely to attack middle-aged persons.The tumor mainlymanifests as muscle weakness and sensor abnormalities.Microscopic examination showed slit-like vascular spaces andoral-or spindle-shaped cells with slightly acidic cytoplasm and oral nuclei.Tumors were subtotally resected in 11 patients,subtotally resected with postoperative radiotherapy in 4,totally resected in 5,and totally resected with postoperativeradiotherapy in 3.Two patients were given spinal stabilization after total resection.Recurrence and metastatic rates were50% and 0 in intradural patients.They were 73% and 27% in extradural patients,respectively.Conclusions The tumor should be resected en bloc with the neighboring dural mater to reduce recurrence andmetastasis.Patients with subtotal resection need adjuvant radiotherapy.Patients with evident spinal involvement maybenefit from spinal stabilization.The prognosis of the lesion arising from the dural mater is better.
Background Primary intraspinal hemangiopericytoma is a rare malignant mesenchymal tumor with high rates ofrecurrence and metastasis. Surgery is the main therapeutic procedure for this lesion. This clinical research wasundertaken to analyze the pathological characteristics, clinical course, and the choice of treatment for this lesion. Methods Twenty-three patients with primary intraspinal hemangiopericytomas were treated from 1987 to 2004. The clinical and imaging features, pathological findings, therapeutic procedures, and prognosis were analyzed retrospectively. Results Primary intraspinal hemangiopericytoma is more likely to attack middle-aged persons. The tumor mainlymanifests as muscle weakness and sensor abnormalities. Microscopic examination showed slit-like vascular spaces andoral-or spindle-shaped cells with slightly acidic cytoplasm and oral nuclei. Tumors were subtotally resected in 11 patients, subtotally resected with postoperative radiotherapy in 4, totally resected in 5, and totally resec ted with postoperativeradiotherapy in 3. Two patients were given spinal stabilization after total resection. Recurrence and metastatic rates were 50% and 0 in intradural patients. They were 73% and 27% in extradural patients, respectively. Conclusions The tumor should be resected en bloc with the neighboring dural mater to reduce recurrence andmetastasis.Patients with subtotal resection need adjuvant radiotherapy. Patients with evident spinal involvement maybenefit from spinal stabilization. prognosis of the lesion arising from the dural mater is better.