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女性尿道及阴道是对雌激素敏感的组织,均来源于泌尿生殖窦,在结构和胚胎发生上有密切联系,均载有雌激素受体。绝经后数年内因雌激素水平降低,尿道及阴道萎缩,粘膜变薄,可发生或加重真性应力性尿失禁(GSUI)。当然给予雌激素治疗也能使尿道粘膜充血变厚,增加尿道压力,使症状有所改善。在此基础上作者通过11例绝经后GSUI 患者每晚使用阴道雌激素霜2g 治疗6周前后的变化,阐明雌激素与临床、尿动力学及尿道细胞学的关系。作者发现雌激素治疗后的 GSUI 患者血
Female urethra and vagina are estrogen-sensitive tissue, are derived from the urogenital sinus, in the structure and the embryo are closely linked, both containing the estrogen receptor. A few years after menopause due to lower estrogen levels, urethral and vaginal atrophy, mucosal thinning, can occur or aggravate true stress incontinence (GSUI). Of course, giving estrogen therapy can also thicken the urethral mucosa congestion, increased urinary tract pressure, so that symptoms have improved. On this basis, the author through the 11 cases of postmenopausal GSUI patients with vaginal estrogen cream 2g per night for 6 weeks before and after the change, clarify the relationship between estrogen and clinical, urodynamic and urethral cytology. The authors found GSUI patient blood after estrogen treatment