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原发性痛经病人子宫肌过多收缩引起子宫缺血和疼痛,Akeslund发现选择性B_(2-)肾上腺受体兴奋剂抑制子宫收缩和增加子宫内膜血流,可解除痛经患者的疼痛,应用抑制前列腺素合成作用的药物治
Akeslund found that selective B_ (2 -) adrenergic receptor agonists inhibit uterine contractions and increase endometrial blood flow in patients with dysmenorrhea due to excessive contraction of the uterine muscles in patients with primary dysmenorrhea, which relieves pain in dysmenorrhea patients. Drugs that inhibit prostaglandin synthesis