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目的:探讨冠状动脉梗死相关病变钙化与临床表现的关系。方法:将经血管内超声(IVUS)检查发现有冠状动脉钙化的患者48例分为两组:急性冠状动脉综合征(ACS)组 28 例、稳定型心绞痛(SAP)组 20 例。对两组患者的冠状动脉梗死相关病变钙化进行测量及分析。结果:ACS组患者血管梗死病变处较SAP组患者相对缺乏,钙化两组的最大钙化弧度分别为(85.48±71.52)°,(152.00±103.08)°, P<0.05。ACS组的钙化斑块比例低于SAP组,57.14%∶83.33%,P<0.05;前者偏心斑块多于后者,93.88%∶54.17%, P<0.01;破裂斑块亦多于后者,42.86%∶8.33%,P<0.01。结论:ACS患者血管梗死病变处较SAP患者相对缺乏钙化,这有助于对ACS发病机制的理解,钙化的存在也有助于识别冠状动脉狭窄病变。
Objective: To investigate the relationship between calcification and its clinical manifestations in patients with coronary artery infarction. Methods: Forty-eight patients with coronary artery calcification undergoing IVUS examination were divided into two groups: 28 patients in acute coronary syndrome (ACS) group and 20 patients in stable angina pectoris group (SAP). Coronary artery infarction-related calcifications in both groups were measured and analyzed. Results: The vascular calcification in patients with ACS was less than that in SAP patients. The maximum calcification radii of calcification group were (85.48 ± 71.52) ° and (152.00 ± 103.08) °, respectively, P <0.05. The percentage of calcified plaque in ACS group was lower than that in SAP group (57.14%: 83.33%, P <0.05). The former had more eccentric plaque than the latter, 93.88% (54.17%), P <0.01; 42.86%: 8.33%, P <0.01. Conclusion: ACS patients with less vascular calcification than those with SAP are helpful to understand the pathogenesis of ACS. The presence of calcification also helps to identify coronary artery stenosis.