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目的探究丙种球蛋白联合光疗治疗新生儿ABO溶血病的临床疗效。方法将60例ABO溶血患儿平均分为研究组与观察组,每组30例。观察组给予白蛋白、苯巴比妥、茵栀黄口服液及蓝光照射治疗。研究组在治疗组的基础上给予丙种球蛋白进行治疗。结果研究组在治疗后无明显的溶血现象,而观察组在治疗前与治疗后仍有溶血存在,两组患儿疗效比较差异有统计学意义(P<0.05)。且研究组黄疸消失的时间明显优于观察组(P<0.05)。结论丙种球蛋白联合光疗治疗新生儿ABO溶血病疗效显著,值得广泛应用于临床。
Objective To investigate the clinical efficacy of gamma globulin combined with phototherapy in the treatment of neonatal ABO hemolytic disease. Methods Sixty children with ABO hemolysis were divided equally into study group and observation group with 30 cases in each group. The observation group was given albumin, phenobarbital, Yinzhihuang oral solution and blue light irradiation treatment. The study group was treated with gamma globulin on the basis of the treatment group. Results The study group had no obvious hemolysis after treatment, while the observation group still had hemolysis before and after treatment. The difference between the two groups was statistically significant (P <0.05). And the study group jaundice disappeared significantly better than the observation group (P <0.05). Conclusion Gamma globulin combined with phototherapy is effective in neonatal ABO hemolytic disease and should be widely used in clinic.