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INTRODUCTION The germ cells are the only cells capable of transmitting genetic and epigenetic information to the next generation and germ cell development in vivo undergoes complex processes to achieve this goal.An effective gamete differentiation model in vitro from pluripotent stem cells has benefits for elucidating the mechanism of the germline cell development and holds promising prospects in treating
INTRODUCTION The germ cells are the only cells capable of transmitting genetic and epigenetic information to the next generation and germ cell development in vivo undergoes complex processes to achieve this goal. An effective gamete differentiation model in vitro from pluripotent stem cells has benefits for elucidating the mechanism of the germline cell development and holds promising prospects in treating