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目的:建立人眼晶状体的功能仿真模型,研究人眼的调节机制。方法:利用临床获得的数据,在计算机上建立晶状体调节的数字仿真模型,根据调节理论进行晶状体形变和调节仿真,并分析眼压对晶状体形变的影响。结果:仿真计算表明,随着调节的增加,前、后表面向远离晶状体中心的方向移动,晶状体厚度增大,前房深度减小;晶状体的前、后表面曲率半径增加,使得屈光力增大。晶状体形态对压力变化敏感:在晶状体表面施加压力后,前、后表面在压力的作用下向赤道部移动,晶状体厚度减小;前后表面曲率半径增大,赤道半径增大;屈光力随着压力的增大而增大。结论:仿真研究支持了 H elmholtz 的调节理论,与公认的调节事实相符合,表明了仿真研究是有效的研究方法。
Objective: To establish a functional simulation model of human lens and to study the regulation mechanism of human eye. Methods: Based on the clinical data, a digital simulation model of lens accommodation was established on the computer. The lens deformation and adjustment simulation was performed according to the adjustment theory. The effect of intraocular pressure on the lens deformation was analyzed. Results: The simulation results show that as the adjustment increases, the anterior and posterior surfaces move away from the center of the lens, the thickness of the lens increases and the depth of the anterior chamber decreases. The curvature radius of the anterior and posterior surfaces of the lens increases and the refractive power increases. The shape of the lens is sensitive to the pressure change: after pressure is exerted on the lens surface, the front and back surfaces move towards the equator under pressure and the lens thickness decreases; the radius of curvature of the front and back surfaces increases and the equatorial radius increases; the refractive power increases with pressure Increase and increase. CONCLUSIONS: Simulation studies support the Holmholtz theory of accommodation, which is consistent with well-established accommodation facts, indicating that simulation studies are effective research methods.