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目的 观察低分子肝素治疗急性脑梗死的临床疗效及对出凝血时间、凝血酶原时间、血小板的影响。方法 6 0例急性脑梗死患者 ,分为治疗组、对照组各 30例。治疗组采用低分子肝素静滴 ,对照组用低分子右旋糖酐治疗。结果 治疗组总有效率 93.3% ,显效率 6 3 .3% ,明显优于对照组 (73.3% ,46 .6 % ) ,有显著性差异 (P <0 .0 1) ;对出凝血时间、凝血酶原时间、血小板无显著性差异 (P >0 .0 5 ) ,无 1例继发出血。结论 低分子肝素治疗急性脑梗死是安全有效的
Objective To observe the clinical effect of low molecular weight heparin in the treatment of acute cerebral infarction and its influence on clotting time, prothrombin time and platelet. Methods Sixty patients with acute cerebral infarction were divided into treatment group and control group with 30 cases each. The treatment group with low molecular weight heparin infusion, the control group with low molecular weight dextran treatment. Results The total effective rate of the treatment group was 93.3%, the effective rate was 63.3%, which was significantly better than that of the control group (73.3%, 46.6%), with significant difference (P <0.01) Prothrombin time, platelet no significant difference (P> 0.05), no one case of secondary bleeding. Conclusion Low molecular weight heparin is safe and effective in the treatment of acute cerebral infarction