论文部分内容阅读
松弛素的主要来源是妊娠黄体,而孕酮来自黄体与胎盘,所以认为松弛素是提供黄体功能的正确指数。前列腺素对动物已公认有溶黄体作用而对人类尚未明确证实。有人报道在足月妊娠时PGF_(2α)并不引起孕妇血清松弛素的变化,而早期妊娠时尚待确定。本文报道PGE_1的衍生物16,16-双甲基-反式Δ~2-PGE_1甲酯(简称16DM-PGE_1),抗早孕时孕妇血清松弛素水平明显升高。 11例孕妇用16DM-PGE_1抗早孕,平均年龄31岁(16～41),平均孕周是9周(7～13),平均孕次1.2(0～3),用16DM-PGE_1栓剂1mg放入阴道后穹窿,在用药前1小时与用药时先抽二次血标本。如无阴道出血则每3小时放栓剂一枚,最
The main source of relaxin is the corpus luteum, while the progesterone is derived from the corpus luteum and the placenta, so relaxin is considered the correct index to provide corpus luteum function. Prostaglandins have been well-established in animals and have not yet been clearly demonstrated in humans. It has been reported that PGF_ (2α) does not cause changes in serum relaxin in pregnant women at term of pregnancy, but this is still to be confirmed at early pregnancy. In this paper, 16,16-bis-methyl-trans-2-PGE 1 methyl ester (16DM-PGE 1), a derivative of PGE 1, was reported. The level of serum relaxin in pregnant women was significantly increased during anti-pregnancy. The average gestational age was 31 weeks (ranged from 16 to 41). The mean gestational age was 9 weeks (range, 7 to 13), with an average of 1.2 (0 to 3) pregnancies. The patients were treated with 16DM-PGE1 suppository Vaginal posterior fornix, 1 hour before medication and medication when the first two blood samples. If no vaginal bleeding suppository every 3 hours, most