论文部分内容阅读
目的:观察不同抑酸药对高血压脑出血并发胃肠出血的预防作用.方法:116例高血压脑出血患者随机分为奥美拉唑组、法莫替丁组、无抗酸药组,观察治疗期间发生胃肠出血的例数.结果:三组胃肠出血的发生率分别为,奥美拉唑组2.9%,法莫替丁组5.4%,无抗酸药组30%.奥美拉唑组发生率与法莫替丁组相近,两组比较无显著差异性(P>0.05).该两组与无抗酸药组分别比较,发生率明显低于无抗酸药组(P<0.01).结论:抗酸药的预防性应用能有效地防止并发胃肠出血的发生.
Objective: To observe the preventive effect of different antacids on hypertensive intracerebral hemorrhage complicated with gastrointestinal bleeding.Methods: One hundred and sixteen patients with hypertensive intracerebral hemorrhage were randomly divided into omeprazole group, famotidine group, antacid-free group, The incidence of gastrointestinal bleeding during the treatment period was observed.Results The incidence of gastrointestinal bleeding in the three groups were 2.9% in the omeprazole group, 5.4% in the famotidine group and 30% in the non-antacid group, respectively. The incidence of pyrazole group was similar to that of famotidine group, and there was no significant difference between the two groups (P> 0.05). The incidence of pyrazole group was significantly lower than that of antacid group <0.01) .Conclusion: The prophylactic use of antacids can effectively prevent the occurrence of gastrointestinal bleeding.