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目的探讨支气管肺泡灌洗液(BALF)中癌胚抗原(CEA)测定对周围型肺癌的诊断价值。方法采用免疫放射分析法(IRMA)测定27例周围型肺癌患者和18例肺良性病变患者BALF和血清中CEA的水平。结果肺癌组BALF和血清中CEA明显高于肺良性疾病组,差异有统计学意义(P<0.05);肺癌组BALF中CEA水平高于血清中,差异有统计学意义(P<0.05)。结论BALF中CEA对于鉴别诊断周围型肺癌、肺部良性疾病有较好的临床价值。
Objective To investigate the diagnostic value of carcinoembryonic antigen (CEA) in bronchoalveolar lavage fluid (BALF) in peripheral lung cancer. Methods The levels of CEA in BALF and serum were determined by radioimmunoassay (IRMA) in 27 patients with peripheral lung cancer and 18 patients with benign lung disease. Results The CEA of BALF and serum in lung cancer group was significantly higher than that in benign lung disease group (P <0.05). The CEA level in BALF in lung cancer group was significantly higher than that in serum (P <0.05). Conclusions CEA in BALF has good clinical value in the differential diagnosis of peripheral lung cancer and benign lung diseases.