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为探讨天门冬的抗衰老机制，采用Ｄ－半乳糖衰老模型小鼠，观察其对脑ＳＯＤ、ＭＤＡ、Ｎａ＋、Ｋ＋－ＡＴＰａｓｅ对红细胞膜、肝细胞膜ＭＤＡ、Ｎａ＋、Ｋ＋－ＡＴＰａｓｅ，对睾丸线粒体ＧＳＨ－Ｐｘ、ＭＤＡ、Ｎａ＋、Ｋ＋－ＡＴＰａｓｅ的影响；结果表明：天门冬乙醇提取液可显著提高衰老模型小鼠脑ＳＯＤ、ＭＤＡ、Ｎａ＋、Ｋ＋－ＡＴＰａｓｅ活力，降低ＭＤＡ含量（Ｐ＜０．０１）；可显著提高肝细胞膜Ｎａ＋、Ｋ＋－ＡＴＰａｓｅ活力，降低ＭＤＡ含量（Ｐ＜０．０１）；可显著提高睾丸线粒体ＧＳＨ－Ｐｘ、Ｎａ＋、Ｋ＋－ＡＴＰａｓｅ活力（Ｐ＜０．０１），降低ＭＤＡ含量（Ｐ＜０．０５）。
In order to investigate the anti-aging mechanism of Asparagus, D-galactose-senescence model mice were used to observe the SOD, MDA, Na+, K+-ATPase in the brain to erythrocyte membrane, liver cell membrane MDA, Na+, K+-ATPase, and to the testis mitochondria GSH Effects of Px, MDA, Na+ and K+-AT-Pase; The results showed that the ethanol extract of Asparagus can significantly increase the activities of SOD, MDA, Na+ and K+-ATPase in the brain of aging mice and reduce the content of MDA (P<0. 01); can significantly increase the Na +, K +-ATPase activity of liver cells, reduce MDA content (P <0.01); can significantly increase the testicular mitochondria GSH-Px, Na +, K +-ATPase activity (P <0.01), decreased MDA content (P<0.05).