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目的研究分析恶性血液病并发下肢深静脉血栓形成情况。方法选取该院收治的15例恶性血液病并发下肢深静脉血栓患者为研究对象(2015年2月—2016年8月收治)。比较分析临床资料和形成原因,10例患者DVT累及部位为左下肢,9例患者累及部位为左下肢。根据患者实际情况,给予非手术治疗,卧床休息,抬高患者患肢,膝关节处于屈曲位,从而降低发生肺拴塞及急性期水肿情况。给予患者低分子肝素治疗,皮下注射,1次/d,4 000 U/次,治疗时间为11~14 d,尿激酶20万U/次,溶于5%葡萄糖溶液,静脉滴入,1次/d,治疗时间为7~10 d。在治疗过程中,应密切关注患者相关反应。结果经过对应的治疗后,15例患者中,肢体肿胀情况完全消失患者为11例,消肿时间范围为4~13 d,另4例患者肢体肿胀程度也有一定减轻。治疗过程中,15例患者均未出现肺拴塞或出血倾向。结论恶性血液病并发下肢深静脉血栓形成严重降低患者生活质量,需及时给予相应治疗,缓解患者临床症状。
Objective To study the analysis of hematologic malignancies complicated by deep vein thrombosis. Methods Fifteen cases of hematologic malignancies complicated with deep venous thrombosis of lower extremities were selected as the study subjects (February 2015-August 2016). Comparative analysis of clinical data and the reasons for the formation, DVT of 10 patients with left lower extremity involvement, and 9 patients with left lower extremity involvement sites. According to the actual situation of patients, given non-surgical treatment, bed rest, raising the patient’s limbs, knee flexion, thereby reducing the incidence of pulmonary embolism and acute edema. Patients given low molecular weight heparin treatment, subcutaneous injection, 1 / d, 4 000 U / time for treatment of 11 ~ 14 d, urokinase 200,000 U / times, dissolved in 5% glucose solution, / d, the treatment time is 7 ~ 10 d. In the course of treatment, should pay close attention to patient-related reactions. Results After the corresponding treatment, in 15 patients, limb swelling completely disappeared in 11 patients, swelling time range of 4 ~ 13 d, and the other 4 patients had some degree of limb swelling reduced. During the course of treatment, none of the 15 patients developed any tendency of pulmonary embolism or bleeding. Conclusions Malignant hematological diseases complicated with deep venous thrombosis of lower extremities may seriously degrade the quality of life of patients. Corresponding treatment should be given in time to alleviate the clinical symptoms.