Active Oxygen Radical Scavenging Ability of Water-Soluble β-Alanine C_(60) Adducts

来源 :Chinese Chemical Letters | 被引量 : 0次 | 上传用户:winston69
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Water-soluble b-alanine C60 adducts were synthesized, and the scavenging ability to superoxygen anion radical O2- and hydroxyl radical.OH were studied by autoxidation of pyrogallol and chemiluminescence, respectively. It was found thatβ-alanine C60 adducts showed an excellent efficiency in eliminating superoxygen anion radical and hydroxyl radical. The 50% inhibition concentration (IC50) for superoxygen anion radical and hydroxyl radical were 0.15 mg/mL and 0.048 mg/mL, respectively. The difference should be mainly attributed to the different scavenging mechanisms. Water-soluble b-alanine C60 adducts were synthesized, and the scavenging ability to superoxygen anion radical O2- and hydroxyl radical. OH were studied by autoxidation of pyrogallol and chemiluminescence, respectively. It was found that β-alanine C60 adducts showed an excellent efficiency in Eliminating superoxygen anion radical and hydroxyl radical. The 50% inhibition concentration (IC50) for superoxygen anion radical and hydroxyl radical were 0.15 mg / mL and 0.048 mg / mL, respectively. The difference should be mainly attributed to the different scavenging mechanisms.
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