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目的:回顾29 例髓母细胞瘤术后放疗,对影响生存情况的因素进行分析。方法:手术后病理证实的29例髓母细胞瘤,先行卡氮芥(BCNU)化疗,再行60钴常规分割照射:全脑剂量(DT)22~40 Gy;原发病灶追加DT15~22 Gy;全脊髓轴DT25~35 Gy。结果:1、3、5、8 年生存率分别为89.6% (26/29)、55.2% (16/29)、30.4% (7/23)、25.0% (4/16)。结论:病人生存期长短与手术切除范围、术后接受放疗时间、放射剂量及是否行化疗有关。
Objective: To review the postoperative radiotherapy of 29 cases of medulloblastoma and to analyze the factors affecting the survival. METHODS: Twenty-nine cases of medulloblastoma confirmed by pathology were treated with BCNU chemotherapy and followed by 60 cobalt conventional fractionation (DT) of 22-40 Gy. Additional primary lesions were treated with DT15-22 Gy ; Spinal axis DT25 ~ 35 Gy. Results: The 1,3,5,8 year survival rates were 89.6% (26/29), 55.2% (16/29), 30.4% (7/23), 25.0% (4) / 16). Conclusion: The survival of patients with surgical resection scope, postoperative radiotherapy time, radiation dose and whether chemotherapy.