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患者男,38岁。1989—04—01因腹泻口服痢特灵200mg,次日开始发热,以后每日体温38℃—39℃,4天时齿龈出血,皮肤大量出血点,黑便,呕血,皮肤出血点逐渐增多。双下肢大量瘀斑,右颊粘膜可见2cm×2cm血泡一个。心肺正常,肝脾未触及。于1989—04—07入院。既往史;1988年—1889年配药治胃溃疡,曾服痢特灵,未用过氯、合霉素,未用过黄胺及解热止痛药,亦无放射线接触史。实验室检查:白细胞1.4×10~9/L,中性18%,淋巴82%。血小板30.0×10~9/L,血红蛋白55g/L,网织细胞0.1%,红细胞1.86×10~(12)/L。骨髓检查:中性粒细胞6.0,晚幼粒细胞5.0,带形核2.0,多形核6.0,淋巴81.0%。骨髓增生呈Ⅱ级,粒系统增生,各期都有
Male patient, 38 years old. 1989-04-01 Because of diarrhea oral furazolidone 200mg, fever the next day, the daily body temperature 38 ℃ -39 ℃, 4 days when bleeding gums, a large number of bleeding spots, melena, hematemesis, skin bleeding points increased. Double lower extremity ecchymosis, right cheek mucosa visible 2cm × 2cm a blood bubble. Cardiopulmonary normal, liver and spleen not touched. In 1989-04-07 admission. Past history; 1988 - 1889 Treatment of gastric ulcer, served furazolidone, no chlorine, chlortetracycline, unused yellow amine and antipyretic analgesics, no history of radiation exposure. Laboratory tests: leukocytes 1.4 × 10 ~ 9 / L, 18% neutral, lymphatic 82%. Platelets 30.0 × 10 ~ 9 / L, hemoglobin 55g / L, reticulocytes 0.1%, erythrocytes 1.86 × 10-12 / L. Bone marrow examination: neutrophil 6.0, late promyelocytic 5.0, band 2.0, polymorphonuclear 6.0, lymph 81.0%. Bone marrow hyperplasia grade Ⅱ, granulomatous hyperplasia, all have