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目的:观察普贝生用于产科促宫颈成熟和引产的效果及安全性。方法:2007年9月～2007年12月有引产指征的足月妊娠孕妇56例随机分成两组,研究组33例,以普贝生1枚阴道用药;对照组23例,静滴催产素引产。对促宫颈成熟、引产成功率、分娩情况等进行比较。结果:研究组促宫颈成熟效果明显优于对照组(P<0.05),引产成功率高于对照组,研究组用药至临产时间、第一产程显著短于对照组(P<0.05),对母婴影响无显著差别。结论:普贝生对产科促宫颈成熟和引产安全有效,对母儿无明显不良影响。
OBJECTIVE: To observe the efficacy and safety of puberty in the promotion of cervical maturation and induction of labor in obstetrics. Methods: From September 2007 to December 2007, 56 pregnant women of full-term pregnancy who had induction of labor induction were randomly divided into two groups. The study group consisted of 33 patients with 1 pessary vaginal drug. In the control group, 23 patients received intravenous oxytocin Induction. To promote cervical ripening, induction of labor success rate, childbirth and so on were compared. Results: In the study group, cervical ripening was significantly better than that in the control group (P <0.05). The success rate of induction of labor was higher in the study group than in the control group. The study group was significantly shorter than the control group (P <0.05) No significant difference in infant effects. Conclusion: Pu Beisheng is safe and effective for obstetrics to promote cervical ripening and induction of labor, and has no obvious adverse effect on maternal and child.