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疟疾休止期根治是进一步肃清传染源的重要措施之一。国内作疟疾休止期治疗,大都采用伯氨喹啉180mg 和乙氨嘧啶100mg 并用的八天疗法。实践证明,这种疗法效果较好,但由于服药时间长,不易坚持到底,两药并用又增加了药物反应,从而影响了服药质量,降低了抗疟效果。为此,开封地区从1977年在全区十个县大面积使用单剂量伯氨喹啉150mg 连服五天的疗法作疟疾休止期根治,至1983年已经使用七年,在这七年中不论上半年疟疾复发和下半年疟疾发病,都在
Malaria cure is one of the important measures to further eliminate the source of infection. Ceiling for the domestic treatment of malaria, mostly used primaquine 180mg and 100 mg of pyrimethamine and eight days of treatment. Practice has proved that the effect of this therapy is better, but due to taking a long time, not easy to persist in the end, the two drugs combined with increased drug response, thus affecting the quality of medication, reducing the anti-malarial effect. To this end, the Kaifeng area was used as a malaria suspension period for the large-scale single-dose therapy with 150 mg of primaquine 150 mg for five days in ten counties throughout the region in 1977 and seven years after 1983, Malaria recurred in the first half year and malaria incidence in the second half year