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目的 观察负压封闭引流(vacuum sealing drainage,VSD)技术用于治疗腹股沟疝修补术后补片感染的临床效果.方法 回顾性收集2012年2月至2015年12月期间笔者所在医院收治的腹股沟疝修补术后发生补片感染的24例病例,根据治疗方式将患者分为2组:VSD组12例(13侧),给予VSD治疗;常规组12例(13侧),给予常规换药处理.比较2组患者的补片保留情况、切口愈合时间、住院费用及住院时间.结果 VAS组和常规组患者的补片保留率[76.9% (10/13)比30.8% (4/13)]、切口愈合时间[(20.5±4.4)d比(29.7±6.7)d]、治疗费用[(18 430.1±7 180.2)元比(12 201.1±6 453.2)元]及住院时间[(23.5±4.1)d比(30.7±6.5)d]比较差异均有统计学意义(P< 0.050),VSD组的补片保留率高,切口愈合时间和住院时间短,治疗费用高.结论 VSD能够有效控制腹股沟疝修补术后补片感染,提高补片保留率,并能够促进创腔内肉芽组织生长,缩短创面愈合时间及住院时间,但费用较常规换药高.“,”Objective To observe the clinical effect of vacuum sealing drainage (VSD) in the treatment of mesh infection following inguinal hernia repair.Methods A total of 24 patients who suffered form mesh infection following inguinal hernia repair and got treatment in our hospital from February 2012 to December 2015 were collected and divided into 2 groups according to the type of treatment,12 patients (13 sides) of VSD group received treatment of VSD,and 12 patients (13 sides) of conventional group received conventional treatment.Comparison between the 2 groups in mesh retention rate,the wound healing time,hospitalization cost,and hospital stay was performed.Results There was significant difference in mesh retention rate [76.9% (10/13) vs.30.8% (4/13)],the wound healing time [(20.5±4.4) d vs.(29.7± 6.7) d],hospitalization cost ((18 430.1±7 180.2) RMB vs.(12 201.1±6 453.2) RMB],and hospital stay [(23.5±4.1) d vs.(30.7±6.5) d] between the VSD group and conventional group (P<0.050).Compared with conventional group,the mesh retention rate and hospitalization cost were higher,the wound healing time and hospital stay were shorter in VSD group.Conclusions VSD can effectively control the mesh infection following hernia repair,improve the mesh retention rate.The VSD can also promote growth of granulation tissue in cavity,shorten the wound healing time and hospital stay,but has a high hospitalization cost than conventional treatment.