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本文首次就胰岛素抵抗综合征对非糖尿病老人罹患冠心病(CHD)意外的预测价值进行了大宗分析。对象与方法1069例非糖尿病老人,男396例,女673例,年龄65～74岁。研究中均接受标准口服葡萄糖耐量试验,藉以评测空腹及餐后2h血糖、血胰岛素水平。同时测定血脂、尿白蛋白、尿白蛋白/尿肌酐比值(ACR)。嗣后人均随访7年,观察分析公认的CHD诸危险因素、胰岛素抵抗综合征以及ACR等与老年人罹发CHD意外(典型心绞痛、非致命性AMI和CHD死亡)危险间的关系。
This is the first major analysis of the predictive value of insulin resistance syndrome in non-diabetic elderly with coronary heart disease (CHD) accidents. Objects and Methods 1069 non-diabetic elderly, 396 males and 673 females, aged 65 to 74 years. The study were to accept the standard oral glucose tolerance test, in order to assess fasting and 2h postprandial blood glucose, blood insulin levels. Blood lipid, urinary albumin, urinary albumin / urinary creatinine ratio (ACR) were measured at the same time. The follow-up was followed up for 7 years. The prevalence of CHD risk factors such as CHD, insulin resistance syndrome, ACR, and the risk of CHD accidents (typical angina pectoris, non-fatal AMI and CHD death) in the elderly were observed and analyzed.