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目的观察主动脉内球囊反搏(IABP)联合经皮冠状动脉介入(PCI)治疗急性心肌梗死合并心源性休克的临床疗效。方法选择2013年5月-2014年6月在医院急诊救治的急性心肌梗死伴心源性休克患者160例,随机分为观察组和对照组各80例,2组患者均进行急诊PCI,观察组在PCI前接受IABP联合药物治疗,对照组在PCI前仅接受药物治疗。比较2组患者的血清N末端B型利钠肽原(NT-pro BNP)、心肌酶含量以及心脏彩色多普勒超声指标。结果观察组患者的NT-pro BNP、肌酸激酶同工酶(CK-MB)、心肌肌钙蛋白(c Tn I)含量以及病死率低于对照组(P<0.05),左室射血分数(LVEF)和左室舒张末径(LVEDD)高于对照组(P<0.05)。结论 IABP联合PCI治疗急性心肌梗死有助于改善神经体液指标、减少心肌细胞损伤、增强心功能,是理想的治疗方法。
Objective To observe the clinical effects of intra-aortic balloon pump (IABP) combined with percutaneous coronary intervention (PCI) in the treatment of acute myocardial infarction complicated with cardiogenic shock. Methods From May 2013 to June 2014, 160 patients with acute myocardial infarction and cardiogenic shock who were hospitalized in the hospital were randomly divided into observation group (80 cases) and control group (80 cases). The two groups were performed emergency PCI and observation group IABP combined with drug treatment before PCI, the control group received only medication before PCI. Serum N-terminal pro-brain natriuretic peptide (NT-pro BNP), myocardial enzyme levels and cardiac color Doppler echocardiography were compared between the two groups. Results The levels of NT-pro BNP, CK-MB and cTn I in the observation group were lower than those in the control group (P <0.05). The left ventricular ejection fraction (LVEF) and left ventricular diastolic diameter (LVEDD) were higher than those in the control group (P <0.05). Conclusion IABP combined with PCI in the treatment of acute myocardial infarction is helpful to improve neurohumoral indexes, reduce cardiomyocyte injury and enhance cardiac function, which is an ideal treatment method.