避孕药为何失灵

• 出 处: 农村实用技术与信息
• 发表日期: 1997年11期
• 关键词: 镇静安眠药 肝细胞 要服 配伍禁忌 血液循环 激活酶 解热镇痛药 肝酶诱导剂 保泰松 新诺明

有位一直坚持服用避孕药的妇女,近来怀孕了,她迷惑不解:按时服药,怎么会怀孕呢?医生经过详细询问,方知她最近失眠,每晚要服2片“安定”方能入睡。“安定”正是导致避孕药“失灵”的祸根。 原来,口服避孕药也和其他药物一样有配伍禁忌。口服避孕药进入血液循环首先要经过肝脏处理,肝细胞内有一种使药物降能失效的酶,这种酶在一般情况下催化率并不高。然而镇静安眠药却能激活酶的活性,从而加速了对口服避孕药的破坏与排泄作用。

A woman who has always insisted on taking birth control pills, recently pregnant, puzzled: medication on time, how pregnant? Doctor asked after a detailed inquiry, she was recently insomnia, night to serve 2 “stable” before falling asleep . “Stability” is the curse of “failure” of birth control pills. It turned out that oral contraceptives and other drugs have the same compatibility taboo. Oral contraceptives into the blood circulation first go through the liver, liver cells have a drug to disable energy failure of the enzyme, the enzyme in general, the catalytic rate is not high. However, sedative sleeping pills can activate enzyme activity, thus accelerating the destruction and excretion of oral contraceptives.