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依据辐射防护剂作用的受体理论,药物代谢酶的抑制剂应增强小剂量辐射防护剂的效果,而对大剂量防护效应没有影响。实验者使用高效和特异性的2-丙炔胺类单胺氧化酶(MAO)抑制剂Pargyline及其衍生物选择性MAOA抑
Based on the receptor theory of radioprotective agents, inhibitors of drug-metabolizing enzymes should enhance the efficacy of low-dose radioprotective agents with no effect on high-dose protective effects. The experimenter used the highly selective and specific 2-propynyl amine monoamine oxidase (MAO) inhibitor Pargyline and its derivatives as selective MAOA inhibitors