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目的观察和分析老年人椎—基底动脉供血不足(VBI)患者血流动力学和血液流变学的变化特点。方法对125例VBI患者采用经颅多普勒超声仪(TCD)检测椎动脉(VA)、基底动脉(BA)、大脑前动脉(MCA)、大脑中动脉(ACA)、大脑后动脉(PCA)的收缩峰值血流速度(Vs)、舒张期末血流速度(Vd)。应用全自动血流测定仪测定全血粘度高、中、低切变率,血浆粘度,红细胞压积(HCT)和血沉(ESR)。结果本组TCD检查结果与正常老年组比较,除ACAVs、PCAVd差异无统计学意义,其余各血管检测数据比较差异均有统计学意义。血液流变学表现全血粘度呈增高现象。结论TCD和血液流变学检测方法和结果可作为VBI的首检手段和诊断依据。
Objective To observe and analyze the changes of hemodynamics and hemorheology in elderly patients with vertebro-basilar insufficiency (VBI). Methods Transcranial Doppler (TCD) was used to detect the changes of vertebral artery (VA), basilar artery (BA), anterior cerebral artery (MCA), middle cerebral artery (ACA), posterior cerebral artery (PCA) Peak systolic velocity (Vs) and end diastolic velocity (Vd). Whole blood viscosity, medium and low shear rate, plasma viscosity, hematocrit (HCT) and erythrocyte sedimentation rate (ESR) were measured by automatic blood flow analyzer. Results The results of TCD examination in this group compared with the normal elderly group, except for the ACAVs, PCAVd no significant difference, the rest of the blood test data were statistically significant differences. Hemorheology showed increased whole blood viscosity. Conclusion TCD and hemorheological methods and results can be used as the first detection means and diagnosis basis of VBI.